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Abstract

Pseudomonas aeruginosa is a type of bacteria that is found commonly in the environment, like in soil and in water. This bacteria can cause infections in the blood, lungs (pneumonia), or other parts of the body after surgery. These bacteria are constantly finding new ways to avoid the effects of the antibiotics used to treat the infections they cause. Zinc oxide nanoparticles' (ZnO-NPs') or Nano zinc oxide antibacterial properties have drawn a lot of attention from around the world, especially since nanotechnology has been used to create particles in the nanometer range. Because of their larger specific surface area and improved particle surface reactivity as a result of their smaller particle size, ZnO-NPs have appealing antibacterial qualities. ZnO is a bio-safe substance that affects chemical and biological species through photo-oxidizing and photocatalysis. The Aim of study is to evaluate the antibacterial activity and antibiofilm of Zinc Oxide Nanoparticles (ZnO NPs) against many bacteria isolated from burn infection include P. aeruginosa and S. aureus and Klebsiella. The tests in this study focusing on antibacterial and antibiofilm activity of zinc oxide nanoparticles. The results showed a moderate antibacterial activity by nano zinc oxide where 40% of P. aeruginosa isolates as inhibited, Klebsiella was unaffected, and S. aureus was inhibited. On the other hand, it was exhibit a good antibiofilm activity produced by Pseudomonas aeruginosa and Klebsiella, so the nano zinc oxide shows promise as a potent antibiofilm agent

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