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Al-Bahir Journal for Engineering and Pure Sciences

Abstract

The CRISPR/Cas9 system is a revolutionary genome-editing tool that enables precise and inheritable modifications, transforming plant genetic engineering. Previous literature has indicated that, in agriculture, CRISPR has improved crop yield, biofortification, and resistance to environmental stressors, fostering resilient and high-yielding crops essential for sustaining a growing global population. In nutraceuticals, CRISPR has enhanced the biosynthesis of bioactive compounds such as anthocyanins, flavonoids, and omega-3 fatty acids, improving the nutritional and therapeutic value of crops.

Despite its immense potential, CRISPR technology faces technical, ethical, and regulatory challenges, including off-target effects, accessibility concerns, and public acceptance. Addressing these issues is crucial for its sustainable adoption. Future innovations, including the integration of CRISPR with complementary technologies, will further improve its precision and accessibility, which will facilitate advancements in food security and in the nutraceutical industry. This review aims to explore the applications of CRISPR in enhancing food security and nutraceutical development, assess its impact on crop improvement, and discuss the challenges associated with its adoption.

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